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RESEARCH PUBLICATIONS

2024:

  • Khushboo Rani, Akanksha Gotmare, Andreas Maier, Ruchira Menghal, Nashat Akhtar, Nupur Fangaria, Johannes Buchner and Sunanda Bhattacharyya*. Identification of a chaperone-code responsible for Rad51-mediated genome repair. JBC, 2024, doi: 10.1016/j.jbc.2024.107342.

2023:

  • Priyanka Singh, Wahida Tabassum, Nupur Fangaria, Sandeep Dey, Siladitya Padhi, Mrinal Bhattacharyya, Kota Arun Kumar, Arijit Roy, and Sunanda Bhattacharyya*. Plasmodium Topoisomerase VIB and Spo11 constitute functional type IIB topoisomerase in malaria parasite and its possible role in mitochondrial DNA segregation, mSpectrum 2023, https://doi.org/10.1128/spectrum.04980-22.

2022:

  • Nupur Fangaria, Khushboo Rani, Priyanka Singh, Sandeep Dey, Kota Arun Kumar and Sunanda Bhattacharyya*. DNA damage-induced nuclear import of HSP90α is promoted by Aha1, Molecular Biology of the Cell 2022, doi.org/10.1091/mbc.E21-11-0554.

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  • Priyanka Singh, Khushboo Rani, Akanksha Gotmare and Sunanda Bhattacharyya*. A tale of Topoisomerases and the knotty genetic material in the backdrop of Plasmodium biology, Bioscience Reports, (Invited Review) 2022, 42 (6): BSR20212847.

2021:

  • Wahida Tabassum, Priyanka Singh, Niranjan Suthram, Sunanda Bhattacharyya*, Mrinal Kanti Bhattacharyya*. Synergistic Action between PfHsp90 Inhibitor and PfRad51 Inhibitor Induces Elevated DNA Damage Sensitivity in the Malaria Parasite, Antimicrobial Agents and Chemotherapy, 2021, 65 (9), DOI: 10.1128/AAC.00457-21.

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  • Shephali Bansod, Navya Raj, Amjesh R, Achutshankar S. Nair and Sunanda Bhattacharyya*. Molecular docking and molecular dynamics simulation identify a novel Radicicol derivative that predicts exclusive binding to Plasmodium falciparum Topoisomerase VIB. Journal of Biomolecular Structure and Dynamics, 2021 doi: 10.1080/07391102.2021.1891970.

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  • Payal Jha, Abhilasha Gahlawat, Sunanda Bhattacharyya, Sandeep Dey, Kota Arun Kumar, Mrinal Kanti Bhattacharyya*. Bloom Helicase Along with Recombinase Rad51 Repairs the Mitochondrial Genome of the Malaria Parasite, 2021, https://doi.org/10.1128/mSphere.00718-21.

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  • Wahida Tabassum, Sunanda Bhattacharyya, Shalu M. Varunan and Mrinal K Bhattacharyya*. Febrile temperature causes transcriptional down-regulation of Plasmodium falciparum Sirtuins through Hsp90 dependent epigenetic modification. Molecular Microbiology, 2021,  https://doi.org/10.1111/mmi.14692.

2020:

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  • Niranjan Suthram, Siladiyta Padhi, Payal Jha, Sunanda Bhattacharyya, Gopalakrishnan Bulusu, Arijit Roy, and Mrinal Bhattacharyya*. Elucidation of DNA repair function of PfBlm and potentiation of artemisinin action by a small-molecule inhibitor of RecQ helicase. mSphere, 2020, doi: 10.1128/mSphere.00956-20.

2019:

  • Tanvi Suhane, Vijayalakshmi Prasad, Nupur Fangaria, Achutsankar S. Nair, Wahida   Tabassum, Poorvaja Muley, Mrinal K. Bhattacharyya and Sunanda Bhattacharyya*. Glu-108 in ScRad51 is critical for DNA damage induced nuclear function mSphere, 2019, https://doi.org/10.1128/mSphere.00082-19.

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  • Pratap Vydyam, Dibyendu Dutta, Niranjan Sutram, Sunanda Bhattacharyya and Mrinal Kanti Bhattacharyya*. A Small molecule inhibitor of DNA recombinase Rad51 from Plasmodium falciparum synergizes with the anti-malarial drugs artemisinin and chloroquine. Journal of Biological Chemistry, 2019 294(20):8171-8183. Doi: 10.1074/jbc.RA118.005009.  

2018:

  • Nidhi Khurana, Sayan Bakshi, Wahida Tabassum, Mrinal K. Bhattacharyya and Sunanda Bhattacharyya*. Hsp90 is essential for Chl1 mediated chromosome segregation and sister chromatid cohesion. mSphere, 2018, doi: 10.1128/mSphere.00225-18, 2018.

2017:

  • Payal Jha, Shyamasree Laskar, Swati Dubey, Mrinal K Bhattacharyya* and Sunanda     Bhattacharyya*. Plasmodium Hsp40 and human Hsp70: A potential cochaperone chaperone complex. Molecular and Biochemical Parasitology 214 (10-13) 2017.

2016:

  • Nidhi Khurana, Shyamasree Laskar, Mrinal K. Bhattacharyya and Sunanda Bhattacharyya*. Hsp90 induces increased genomic instability towards DNA damaging agents by tuning down RAD53 transcription. Molecular Biology of the Cell doi: 10.1091/mbc. E15-12-0867, 2016.

  • Sureshkumar Chalapareddy, Swati Chakrabarti, Mrinal K. Bhattacharyya, and Sunanda Bhattacharyya*. Radicicol mediated inhibition of Topoisomerase VIB-VIA activity of human malaria parasite Plasmodium falciparum. mSphere doi:10.1128/mSphere.0002515, 2016. [F1000 Prime Recommended]

2015:

2014:

  • Shyamasree Laskar, Sheeba K, Mrinal K. Bhattacharyya, Achuthsankar S. Nair, Pawan Dhar, Sunanda Bhattacharyya*. Heat stress induced Cup9 dependent transcriptional regulation of Sir2. Molecular and Cellular Biology doi:10.1128/MCB.01046-14, 2014.

  • Tanvi Suhane, Shyamasree Laskar, Siddheshwari Advani, Nabamita Roy, Shalu Varunan, Dibyendu Bhattacharyya, Sunanda Bhattacharyya*, Mrinal Kanti Bhattacharyya*. Both charged linker region and ATPase domain of Hsp90 are essential for Rad51 dependent DNA repair. Eukaryotic Cell doi:10.1128/EC.00159-14, 2014.

  • Suresh Chalapareddy, Mrinal Kanti Bhattacharyya, Seema Mishra, Sunanda Bhattacharyya*. Radicicol confers mid schizont arrest by inhibiting mitochondrial replication in Plasmodium falciparum. Antimicrobial Agents and Chemotherapy AAC.02519-13, 2014.

  • Nabamita Roy, Sunanda Bhattacharyya, Swati Chakrabarty, Shyamasree Laskar, Somepalli Mastan Babu and Mrinal Kanti Bhattacharyya. Dominant negative mutant of Plasmodium Rad51 causes reduced parasite burden in host by abrogating DNA double strand break repair. Molecular Microbiology 94: 2, (353–366), 2014.

2013:

  • Shalu M. Varunan, Jaishree Tripathi, Sunanda Bhattacharyya, Tanvi Suhane, Mrinal Kanti Bhattacharyy. Plasmodium falciparum origin recognition complex subunit 1 (PfOrc1) functionally complements Δsir3 mutant of Saccharomyces cerevisiae. Molecular and Biochemical Parasitology 191: (28– 35), 2013.

2012:

  • Sita Swati Achanta, Shalu M. Varunan, Sunanda Bhattacharyya and Mrinal Kanti Bhattacharyya. Characterization of Rad51 from apicomplexan parasite Toxoplasma gondii: an implication for inefficient gene targeting. PloS ONE 7(7): e41925, 2012.

  • Abhishek Mazumder, Sumita Bandyopadhyay, Dale Lewis, Amlanjyoti Dhar, Sunanda    Deb, Sucharita Dey, Pinak Chakrabarti, Sankar Adhya and Siddhartha Roy, A Genetic Network that Balances Two Outcomes Utilizes Asymmetric Recognition of Operator Sites. Biophysical Journal, 102: 1580-1589, 2012.

2011:

  • Shyamasree Laskar, M. K. Bhattacharyya, Rama Shankar, Sunanda Bhattacharyya*, Hsp90 controls Sir2 mediated gene silencing. PLoS ONE 6(8): e23406, 2011.

2010:

  • Charles A. Miller III, Xiaobing Tan, Mark Wilson, Sunanda Bhattacharyya, Sara Ludwig. Single plasmids expressing human steroid hormone receptors and a reporter gene for use in yeast signaling assays. Plasmid 63: 73–78, 2010.

Previous:

  1. M. K. Bhattacharyya#, Sunanda Bhattacharyya# (nee Deb), Jayabalasingham, B. and Kumar, N. Characterization of kinetics of DNA-strand exchange and ATP hydrolysis activities of Plasmodium falciparum recombinase PfRad51. Mol. Biochem. Parasitol. 139: 33-39, 2004. #(Equal authorship).

  2. Sumita Bandyopadhyay, Sunanda Deb, Sudeep Bose and Siddhartha Roy. Half-of-the sites reactivity of F235C lambda-repressor: implications for the structure of the whole repressor. Protein Engineering 15(5): 393-401, 2002.

  3. Nandan K. Jana, Sunanda Deb, Bhabatarak Bhattacharyya, Nitai C. Mandal and Siddhartha Roy. Energetics of cooperative interaction studied using a mutant λ-repressor. Protein Engineering 13(9): 629-33, 2000.

  4. Sunanda Deb, Sumita Bandyopadhyay and Siddhartha Roy. DNA sequence dependent and independent conformational changes in multipartite operator recognition by λ-repressor. Biochemistry 39(12): 3377-3383, 2000.

  5. Sunanda Deb, Sumita Bandyopadhyay and Siddhartha Roy. Spectroscopic study of Y210C lambda repressor: implications for cooperative interaction. Protein Engineering 11(6): 481-7, 1998.

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